Pyroglutamic acid
|
Basic information |
| Metabolite name | Pyroglutamic acid |
 | HMDB0000267 |
 |
C01879 |
 |
7405 |
| Synonyms | Pyroglutamate; |
| No. of studies | 48 |
|
Basic information |
| Metabolite name | Pyroglutamic acid |
| HMDB0000267 |
|
C01879 |
|
7405 |
| Synonyms | Pyroglutamate; |
| No. of studies | 48 |
|
Relationship between Pyroglutamic acid and depression (count: 48) |
| Study | Study Type  |
Comparison groups | Tissue | Organism | Up/Down regulated |
| Study M001 | Type1 | depressed group vs. control group | Plasma | Human | Down |
| Study M018 | Type1 | CUMS group vs. control group | Serum | Sprague-Dawley rat | Down |
| Study M070 | Type1 | depressed group vs. non-depressed group | Urine | Human | Down |
| Study M075 | Type1 | post stroke depressed group vs. post stroke non-depressed group | Plasma | Human | Up |
| Study M082 | Type3 | medium dose of DG group vs. control group | Hippocampus | C57BL/6J mouse | Down |
| Study M087 | Type2 | ketamine group 2-h vs. baseline | Plasma | Human | Up |
| Study M097 | Type1 | depressed men group vs. control men group | Urine | Human | Down |
| Study M1019 | Type1 | depression group vs. control group | Serum | Human | Down |
| Study M1039 | Type1 | CUMS group vs. control group | Liver | Sprague-Dawley rat | Up |
| Study M107 | Type1 | Glu group vs. control group | PC12 cell medium | Rat | Down |
| Study M107 | Type1 | CORT group vs. control group | PC12 cell medium | Rat | Down |
| Study M1072 | Type1 | CUMS group vs. control group | Plasma | Cynomolgus monkey | Down |
| Study M109 | Type1 | PPD group vs. HC and PPWD group | Urine | Human | Up |
| Study M1090 | Type1 | CUMS group vs. control group | Plasma | BALb/c mouse | Down |
| Study M1090 | Type3 | hyperbaric oxygen treatment group vs. control group | Plasma | BALb/c mouse | Up |
| Study M115 | Type1 | MDD group vs. control group | Plasma | Human | Up |
| Study M130 | Type2 | CSDS + venlafaxine group vs. CSDS group | Prefrontal cortex | C57BL/6 mouse | Down |
| Study M130 | Type2 | CSDS + DG group vs. CSDS group | Prefrontal cortex | C57BL/6 mouse | Down |
| Study M131 | Type1 | CUMS group vs. control group | Hippocampus | Sprague-Dawley rat | Down |
| Study M131 | Type1 | SD group vs. control group | Hippocampus | Sprague-Dawley rat | Up |
| Study M131 | Type1 | CRS group vs. control group | Hippocampus | Sprague-Dawley rat | Up |
| Study M131 | Type1 | LH group vs. control group | Hippocampus | Sprague-Dawley rat | Down |
| Study M207 | Type1 | depressed group vs. control group | Serum | Kunming mouse | Down |
| Study M208 | Type1 | GCI model group vs. control group | Hippocampus | ICR mouse | Down |
| Study M209 | Type1 | CUMS group vs. control group | Hippocampus | Sprague-Dawley rat | Down |
| Study M454 | Type1 | vascular depression model group vs. control group | Hippocampus | ICR mouse | Down |
| Study M460 | Type1 | depressed group vs. control group | Liver | Kunming mouse | Up |
| Study M464 | Type1 | drug-treatment MDD group vs. control group | Plasma | Human | Down |
| Study M464 | Type1 | drug-naive MDD group vs. control group | Plasma | Human | Down |
| Study M486 | Type1 | CORT group vs. control group | PC12 cell medium | Rat | Down |
| Study M512 | Type1 | CUMS group vs. control group | Urine | Goto-Kakizaki rat | Up |
| Study M573 | Type1 | CSDS group vs. control group | Hippocampus | Sprague-Dawley rat | Up |
| Study M602 | Type1 | MDD group vs. control group | Plasma | Human | Up |
| Study M611 | Type1 | LPS group vs. control group | Serum | Sprague-Dawley rat | Unknown |
| Study M633 | Type1 | corticosterone group vs. control group | Urine | C57BL/6 mouse | Down |
| Study M668 | Type1 | PSD group vs. stroke group | Urine | Human | Down |
| Study M683 | Type1 | CUMS group vs. control group | Urine | Sprague-Dawley rat | Up |
| Study M683 | Type2 | CUMS + low dose of Radix Bupleuri and Radix Paeoniae Alba drug pair group vs. CUMS group | Urine | Sprague-Dawley rat | Down |
| Study M683 | Type2 | CUMS + high dose of Radix Bupleuri and Radix Paeoniae Alba drug pair group vs. CUMS group | Urine | Sprague-Dawley rat | Down |
| Study M683 | Type2 | CUMS + middle dose of Radix Bupleuri and Radix Paeoniae Alba drug pair group vs. CUMS group | Urine | Sprague-Dawley rat | Down |
| Study M690 | Type2 | CUMS + high dose of Zhi-zi-chi decoction group vs. CUMS group | Serum | Balb/c mouse | Down |
| Study M691 | Type1 | CUMS group vs. control group | Plasma | Sprague-Dawley rat | Down |
| Study M691 | Type2 | CUMS + low dose of Chaihu-Baishao group vs. CUMS group | Plasma | Sprague-Dawley rat | Up |
| Study M712 | Type1 | depression group vs. control group | Prefrontal cortex | Cynomolgus monkey | Up |
| Study M715 | Type1 | MDD group vs. control group | Faece | Human | Down |
| Study M749 | Type1 | CUMS group vs. control group | Plasma | Cynomolgus monkey | Down |
| Study M769 | Type1 | CSDS group vs. control group | Amygdala | Sprague-Dawley rat | Down |
| Study M772 | Type1 | CUMS group vs. control group | Amygdala | Sprague-Dawley rat | Down |
| Study M867 | Type1 | CUMS group vs. control group | Plasma | Sprague-Dawley rat | Up |
| Study M894 | Type2 | electromagnetic field exposure + heat acclimation group vs. electromagnetic field exposure group | Serum | C57BL/6J mouse | Up |
| Study M911 | Type1 | CUS group vs. control group | Serum | Sprague-Dawley rat | Down |
| Study M912 | Type1 | CUMS group vs. control group | Serum | ICR mouse | Up |
| Study M928 | Type1 | CUMS group vs. control group | Faece | C57BL/6 mouse | Down |
| Study M935 | Type2 | chronic social isolation + tianeptine group vs. chronic social isolation group | Hippocampus | Wistar rat | Up |
| Study M940 | Type1 | CUMS group vs. control group | Cerebral cortex | Sprague-Dawley rat | Down |
| Study M940 | Type2 | CUMS + Chaihu-Baishao herb pair group vs. CUMS group | Cerebral cortex | Sprague-Dawley rat | Up |
| Study M940 | Type2 | CUMS + Chaihu group vs. CUMS group | Cerebral cortex | Sprague-Dawley rat | Up |
| Study M953 | Type1 | CRS group vs. control group | Faece | Sprague-Dawley rat | Up |
| Study M972 | Type1 | CRS + irradiation group vs. control group | Serum | Sprague-Dawley rat | Down |
| Study M972 | Type2 | CRS + irradiation + albiflorin group vs. CRS + irradiation group | Serum | Sprague-Dawley rat | Up |
| Study M972 | Type2 | CRS + irradiation + paeoniflorin group vs. CRS + irradiation group | Serum | Sprague-Dawley rat | Up |
| Study M972 | Type2 | CRS + irradiation + Paeoniae Radix Alba group vs. CRS + irradiation group | Serum | Sprague-Dawley rat | Up |
| Study M975 | Type1 | CUMS group vs. control group | Urine | Sprague-Dawley rat | Up |
| Study M975 | Type2 | CUMS + high dose of Yang-Xin-Jie-Yu Decoction group vs. CUMS group | Urine | Sprague-Dawley rat | Up |
| Study M981 | Type2 | Abeta oligomer + involuntary and voluntary running group vs. Abeta oligomer group | Serum | ICR mouse | Up |
| Study M981 | Type2 | Abeta oligomer + acousto-optic stimulation group vs. Abeta oligomer group | Serum | ICR mouse | Up |