L-Carnitine
|
Basic information |
| Metabolite name | L-Carnitine |
 | HMDB0000062 |
 |
C00318 |
 |
2724480 |
| Synonyms | carnitine |
| No. of studies | 42 |
|
Basic information |
| Metabolite name | L-Carnitine |
| HMDB0000062 |
|
C00318 |
|
2724480 |
| Synonyms | carnitine |
| No. of studies | 42 |
|
Relationship between L-Carnitine and depression (count: 42) |
| Study | Study Type  |
Comparison groups | Tissue | Organism | Up/Down regulated |
| Study M033 | Type3 | paroxetine group vs. control group | Hippocampus | DBA/2OlaHsd mouse | Down |
| Study M072 | Type1 | CUMS group vs. control group | Plasma | Sprague-Dawley rat | Up |
| Study M074 | Type1 | sCSDS group vs. control group | Faece | C57BL/6JJmsSlc mouse | Up |
| Study M081 | Type1 | CUMS group vs. control group | Liver | Wistar rat | Down |
| Study M101 | Type1 | CSD group vs. control group | Faece | C57BL/6 mouse | Down |
| Study M1024 | Type1 | CUMS group vs. control group | Serum | ICR mouse | Up |
| Study M1024 | Type2 | CUMS + hydroxytyrosol group vs. CUMS group | CA3 region of hippocampus | ICR mouse | Down |
| Study M1024 | Type2 | CUMS + hydroxytyrosol group vs. CUMS group | DG region of hippocampus | ICR mouse | Down |
| Study M1024 | Type2 | CUMS + hydroxytyrosol group vs. CUMS group | Serum | ICR mouse | Down |
| Study M104 | Type1 | CUMS group vs. control group | Serum | Sprague-Dawley rat | Down |
| Study M1072 | Type1 | CUMS group vs. control group | Amygdala | Cynomolgus monkey | Down |
| Study M1091 | Type1 | CMS vulnerable group vs. control group | Ventral hippocampus | Wistar rat | Down |
| Study M1092 | Type1 | CMS group vs. control group | Ventral hippocampus | Wistar rat | Down |
| Study M1092 | Type3 | venlafaxine group vs. control group | Ventral hippocampus | Wistar rat | Down |
| Study M1117 | Type1 | MDD group vs. control group, Russian cohort | Plasma | Human | Down |
| Study M148 | Type1 | CUMS group vs. control group | Liver | Wistar rat | Down |
| Study M148 | Type2 | CUMS + CSGS group vs. CUMS group | Liver | Wistar rat | Down |
| Study M148 | Type2 | CUMS + fluoxetine group vs. CUMS group | Liver | Wistar rat | Down |
| Study M207 | Type1 | depressed group vs. control group | Serum | Kunming mouse | Up |
| Study M454 | Type1 | vascular depression model group vs. control group | Hippocampus | ICR mouse | Down |
| Study M472 | Type3 | (2R,6R)-HNK group vs. control group | PC12 cell | Rat | Up |
| Study M472 | Type3 | S-Ket group vs. control group | PC12 cell | Rat | Up |
| Study M472 | Type3 | (2S,6S)-HNK group vs. control group | PC12 cell | Rat | Up |
| Study M472 | Type3 | R-Ket group vs. control group | PC12 cell | Rat | Up |
| Study M512 | Type1 | CUMS group vs. control group | Urine | Goto-Kakizaki rat | Down |
| Study M540 | Type1 | CUMS group vs. control group | Hippocampus | Sprague-Dawley rat | Up |
| Study M578 | Type1 | restraint stress offspring group vs. control offspring group | Hippocampus | Sprague-Dawley rat | Down |
| Study M587 | Type2 | MDD group, after 8-week SSRI treatment vs. before treatment | Plasma | Human | Up |
| Study M648 | Type1 | ART-treated HIV with depressive symptom group vs. ART-treated HIV without depressive symptom group, discovery cohort | Plasma | Human | Down |
| Study M649 | Type1 | depression group vs. control group | Serum | Human | Down |
| Study M669 | Type1 | corticosterone group vs. control group | Liver | C57BL/6J mouse | Up |
| Study M690 | Type2 | CUMS + high dose of Zhi-zi-chi decoction group vs. CUMS group | Serum | Balb/c mouse | Down |
| Study M779 | Type2 | depression group, post vs. before treatment | Plasma | Human | Down |
| Study M806 | Type1 | CUMS group vs. control group | Urine | C57BL/6 mouse | Up |
| Study M806 | Type2 | corticosterone + Gleditsiae spina group vs. corticosterone group | Urine | C57BL/6 mouse | Down |
| Study M818 | Type1 | MDD group vs. control group | Plasma | Human | Up |
| Study M818 | Type2 | MDD group, after 3-month antidepressant treatment vs. baseline | Plasma | Human | Down |
| Study M821 | Type1 | CUMS group vs. control group | Faece | Sprague-Dawley rat | Up |
| Study M823 | Type2 | CUMS + albiflorin group vs. CUMS group | Hippocampus | Sprague-Dawley rat | Up |
| Study M826 | Type1 | CVS group vs. control group | Colorectum | Wistar rat | Up |
| Study M826 | Type1 | CVS group vs. control group | Gut | Wistar rat | Up |
| Study M826 | Type2 | CVS + antibiotic group vs. CVS group | Gut | Wistar rat | Down |
| Study M828 | Type2 | ultrasonic radiation + intraperitoneally clomipramine group vs. ultrasonic radiation group | Hippocampus | Wistar rat | Down |
| Study M839 | Type1 | MDD group vs. control group | Plasma | Human | Down |
| Study M846 | Type2 | postpartum depression model + 919 syrup group vs. postpartum depression model group | Hippocampus | BALB/c mouse | Down |
| Study M847 | Type1 | CUMS group vs. control group | Liver | Sprague-Dawley rat | Up |
| Study M847 | Type2 | CUMS + Bupleuri Radix group vs. CUMS group | Liver | Sprague-Dawley rat | Down |
| Study M850 | Type1 | reserpine group vs. control group | Brain | C57BL/6 mouse | Up |
| Study M856 | Type1 | MDD group vs. control group | Serum | Human | Down |
| Study M856 | Type2 | effective group, post-treatment vs. baseline | Serum | Human | Up |
| Study M858 | Type1 | CUMS group vs. control group | Plasma | Sprague-Dawley rat | Up |
| Study M869 | Type1 | CUMS group vs. control group | Peripheral blood mononuclear cell | Sprague-Dawley rat | Down |
| Study M869 | Type2 | CUMS + middle dose of Chaigui granules group vs. CUMS group | Peripheral blood mononuclear cell | Sprague-Dawley rat | Up |
| Study M869 | Type2 | CUMS + high dose of Chaigui granules group vs. CUMS group | Peripheral blood mononuclear cell | Sprague-Dawley rat | Up |
| Study M882 | Type1 | CUMS group vs. control group | Jejunum | Sprague-Dawley rat | Up |
| Study M890 | Type1 | CUMS group vs. control group | Plasma | Sprague-Dawley rat | Up |
| Study M894 | Type2 | electromagnetic field exposure + heat acclimation group vs. electromagnetic field exposure group | Serum | C57BL/6J mouse | Down |
| Study M928 | Type1 | CUMS group vs. control group | Faece | C57BL/6 mouse | Down |
| Study M972 | Type1 | CRS + irradiation group vs. control group | Cerebral cortex | Sprague-Dawley rat | Up |
| Study M972 | Type2 | CRS + irradiation + Paeoniae Radix Alba group vs. CRS + irradiation group | Cerebral cortex | Sprague-Dawley rat | Down |