Basic information |
Metabolite name | Kynurenic acid/Kynurenine ratio |
N/A | |
N/A | |
N/A | |
Synonyms | kynurenic acid/kynurenine |
No. of studies | 14 |
Relationship between Kynurenic acid/Kynurenine ratio and depression (count: 14) |
Study | Study Type | Comparison groups | Tissue | Organism | Up/Down regulated |
Study M079 | Type1 | acute LPS group vs. control group | Hippocampus | Sprague-Dawley rat | Down |
Study M1029 | Type1 | Crohn’s disease model group vs. control group | Hippocampus | Sprague-Dawley rat | Down |
Study M1029 | Type2 | Crohn’s disease model + 1-methyltryptophan group vs. Crohn’s disease model group | Hippocampus | Sprague-Dawley rat | Up |
Study M1029 | Type2 | Crohn’s disease model + moxibustion + 1-methyltryptophan group vs. Crohn’s disease model group | Hippocampus | Sprague-Dawley rat | Up |
Study M1029 | Type2 | Crohn’s disease model + moxibustion group vs. Crohn’s disease model group | Hippocampus | Sprague-Dawley rat | Up |
Study M1035 | Type2 | mood disorder group, after tryptophan-rich diet vs. baseline | Urine | Human | Up |
Study M166 | Type1 | LPS group vs. control group | Cerebral cortex | Wistar rat | Up |
Study M166 | Type2 | LPS + minocycline group vs. LPS group | Cerebral cortex | Wistar rat | Up |
Study M166 | Type2 | LPS + low dose of Rg1 group vs. LPS group | Cerebral cortex | Wistar rat | Up |
Study M166 | Type2 | LPS + high dose of Rg1 group vs. LPS group | Cerebral cortex | Wistar rat | Up |
Study M190 | Type1 | depressed group vs. control group | Whole blood culture | Human | Down |
Study M489 | Type1 | depression group vs. control group | Serum | Human | Down |
Study M493 | Type1 | depression group vs. control group | Serum | Human | Down |
Study M493 | Type4 | ketamine responder group vs. non-responder group at 24 h and 13 d | Serum | Human | Up |
Study M513 | Type1 | male MDD group vs. male HC group | Serum | Human | Down |
Study M513 | Type1 | female MDD group vs. female HC group | Serum | Human | Down |
Study M518 | Type1 | depression group vs. control group | Plasma | Human | Down |
Study M724 | Type1 | MDD group vs. control group | Serum | Human | Down |
Study M766 | Type1 | CUS group vs. control group | Faece | Sprague-Dawley rat | Up |
Study M879 | Type1 | unipolar depression group vs. control group | Plasma | Human | Down |
Study M976 | Type1 | small intestinal bacterial overgrowth group vs. control group | Urine | Human | Up |
Study M982 | Type1 | adult MDD group vs. adult control group | Plasma | Human | Up |