Basic information |
Metabolite name | Allopregnanolone |
HMDB0001449 | |
C13712 | |
92786 | |
Synonyms | Alloprognanolone |
No. of studies | 7 |
Relationship between Allopregnanolone and depression (count: 7) |
Study | Study Type | Comparison groups | Tissue | Organism | Up/Down regulated |
Study M1131 | Type1 | CUS group vs. control group | Basolateral amygdala | C57BL/6J mouse | Down |
Study M152 | Type1 | CUMS group vs. control group | Hippocampus | Sprague-Dawley rat | Down |
Study M152 | Type1 | CUMS group vs. control group | Amygdala | Sprague-Dawley rat | Down |
Study M152 | Type2 | CUMS + fluoxetine group vs. CUMS group | Hippocampus | Sprague-Dawley rat | Up |
Study M152 | Type2 | CUMS + XYS group vs. CUMS group | Hippocampus | Sprague-Dawley rat | Up |
Study M174 | Type1 | depressed group vs. control group | Plasma | Human | Down |
Study M446 | Type1 | depressed group vs. control group | Cerebrospinal fluid | Human | Down |
Study M446 | Type2 | fluoxetine-treated depressed group post-treatment vs. baseline | Cerebrospinal fluid | Human | Up |
Study M532 | Type1 | MDD group vs. control group | Plasma | Human | Down |
Study M599 | Type1 | PND group vs. control group | Plasma | Human | Up |
Study M712 | Type1 | depression group vs. control group | Intestine | Cynomolgus monkey | Up |