Basic information |
Metabolite name | 5-Hydroxytryptophol |
HMDB0001855 | |
N/A | |
9061 | |
Synonyms | 5-Hydroxyindole acetic acid; |
No. of studies | 6 |
Relationship between 5-Hydroxytryptophol and depression (count: 6) |
Study | Study Type | Comparison groups | Tissue | Organism | Up/Down regulated |
Study M1004 | Type1 | CUMS group vs. control group | Plasma | Sprague-Dawley rat | Up |
Study M1004 | Type1 | CUMS group vs. control group | Hippocampus | Sprague-Dawley rat | Up |
Study M1004 | Type1 | CUMS group vs. control group | Ileum | Sprague-Dawley rat | Up |
Study M1004 | Type2 | CUMS + fluoxetine group vs. CUMS group | Ileum | Sprague-Dawley rat | Down |
Study M1004 | Type2 | CUMS + fluoxetine group vs. CUMS group | Plasma | Sprague-Dawley rat | Down |
Study M1004 | Type2 | CUMS + Zhi-Zi-Chi decoctions group vs. CUMS group | Plasma | Sprague-Dawley rat | Down |
Study M1004 | Type2 | CUMS + Zhi-Zi-Chi decoctions group vs. CUMS group | Ileum | Sprague-Dawley rat | Down |
Study M522 | Type1 | CUMS group vs. control group | Prefrontal cortex | Sprague-Dawley rat | Down |
Study M522 | Type2 | CUMS + NaP group vs. CUMS group | Prefrontal cortex | Sprague-Dawley rat | Up |
Study M523 | Type1 | CUMS group vs. control group | Brain | Wistar rat | Down |
Study M732 | Type1 | CUMS group vs. control group | Hippocampus | Sprague-Dawley rat | Down |
Study M732 | Type1 | CUMS + high dose of propionate group vs. CUMS group | Hippocampus | Sprague-Dawley rat | Up |
Study M758 | Type1 | CUMS group vs. control group | Ventral tegmental area | Sprague-Dawley rat | Down |
Study M758 | Type1 | CUMS group vs. control group | Nucleus accumbens | Sprague-Dawley rat | Down |
Study M758 | Type2 | CUMS + low dose of Shuganheweitang group vs. CUMS group | Prefrontal cortex | Sprague-Dawley rat | Down |
Study M758 | Type2 | CUMS + high dose of volatile oil group vs. CUMS group | Prefrontal cortex | Sprague-Dawley rat | Down |
Study M758 | Type2 | CUMS + high dose of terpenoid group vs. CUMS group | Prefrontal cortex | Sprague-Dawley rat | Down |
Study M758 | Type2 | CUMS + low dose of Shuganheweitang group vs. CUMS group | Nucleus accumbens | Sprague-Dawley rat | Up |
Study M758 | Type2 | CUMS + fluoxetine group vs. CUMS group | Prefrontal cortex | Sprague-Dawley rat | Down |
Study M758 | Type2 | CUMS + low dose of Shuganheweitang group vs. CUMS group | Ventral tegmental area | Sprague-Dawley rat | Up |
Study M994 | Type1 | CUMS group vs. control group | Prefrontal cortex | C57BL/6 mouse | Down |
Study M994 | Type1 | CUMS group vs. control group | Hippocampus | C57BL/6 mouse | Down |
Study M994 | Type2 | CUMS + Uncaria rhynchophylla extract group vs. CUMS group | Prefrontal cortex | C57BL/6 mouse | Up |