Basic information |
Metabolite name | Pregnenolone |
HMDB0000253 | |
C01953 | |
53477678 | |
Synonyms | NA |
No. of studies | 4 |
Relationship between Pregnenolone and depression (count: 4) |
Study | Study Type | Comparison groups | Tissue | Organism | Up/Down regulated |
Study M152 | Type1 | CUMS group vs. control group | Amygdala | Sprague-Dawley rat | Up |
Study M152 | Type2 | CUMS + fluoxetine group vs. CUMS group | Amygdala | Sprague-Dawley rat | Down |
Study M704 | Type3 | low dose of sertraline group vs. control group | Brain | Sprague-Dawley rat | Down |
Study M704 | Type3 | low dose of sertraline group vs. control group | Plasma | Sprague-Dawley rat | Down |
Study M704 | Type3 | middle dose of sertraline group vs. control group | Testis | Sprague-Dawley rat | Down |
Study M704 | Type3 | high dose of sertraline group vs. control group | Adrenal gland | Sprague-Dawley rat | Down |
Study M712 | Type1 | depression group vs. control group | Liver | Cynomolgus monkey | Down |
Study M898 | Type1 | end-stage renal disease with depression group vs. end-stage renal disease without depression group | Serum | Human | Up |