Study M907
Study name | Liu J 2022 |
Title | Combinatorial panel with endophenotypes from multilevel information of diffusion tensor imaging and lipid profile as predictors for depression |
Overall design | The aim of this study was to get a deep insight into the pathophysiology of illness from aspects of the central brain structure and peripheral lipid metabolism. A total of 57 patients with first-episode major depressive disorder (MDD group) and 76 healthy controls (control group) underwent diffusion tensor imaging and plasma lipid profiling. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | DSM-IV diagnosed MDD |
Sample size | 133 |
Tissue | Peripheral; Blood; Plasma; |
Platform | MS-based; LC-MS: Ultimate 3000 ultra-high-performance liquid chromatography coupled with Q Exactive quadrupole-Orbitrap high-resolution mass spectrometer; |
PMID | |
DOI | |
Citation | Liu J, Liu Z, Wei Y, et al. Combinatorial panel with endophenotypes from multilevel information of diffusion tensor imaging and lipid profile as predictors for depression. Aust N Z J Psychiatry. 2022 May 27:48674211031477. |
Metabolite | Linoleic acid; Oleic acid; Stearic acid; Myristic acid; Palmitoleic acid; Palmitic acid; Cholic acid; LysoPC(16:0); LysoPC(18:0); Behenic acid; LysoPC(18:2); TG(58:12); Heptadecanoic acid; Glycocholic acid; LysoPC(15:0/0:0); LysoPE(18:1); Deoxycholic acid glycine conjugate; Taurochenodesoxycholic acid; Deoxycholic acid; 11Z-Eicosenoic acid; LysoPC(20:5); PC(36:4p); TG(58:3); Dehydroepiandrosterone sulfate; Etiocholanolone sulfate; Androsterone sulfate; 13-HODE; 10Z-Heptadecenoic acid; Chenodeoxycholic acid glycine conjugate; 10Z-Nonadecenoic acid; LysoPC(17:0/0:0); LysoPC(16:0e); LysoPC(18:1p); LysoPC(19:0); Cholesterol sulfate; DG(36:2); TG(54:7); LysoPC(20:2); Myristoleic acid; 12,13-DiHODE; TG(50:4); Tricosanoic acid; Tetracosanoic acid; Eicosadienoic acid; FAHFA(18:1(9Z)/10-O-18:0); Tetradecenoic acid isomer; 5Z-Dodecenoic acid; AcCa(14:1); AcCa(16:1); Docosapentaenoic acid (22n-6); SM(d42:3); HETE; TG(45:0); PC(34:2e); LysoPC(18:0e); 5b-Cholestane-3a,7a,12a,23S,25-pentol; TG(53:4); LysoPC(17:1); TG(54:6); |
