Study M121
Study name | Xu HB 2012 |
Title | Potential clinical utility of plasma amino acid profiling in the detection of major depressive disorder |
Overall design | In this study, plasma amino acids profiles were investigated in first-onset treatment-naive depressed patients of short disease duration using a HPLC tandem-mass spectrometric method based on isobaric mass tags (iTRAQ) labeling. Plasma amino acids levels were measured in first-onset treatment-naive depressed patients (depressed group; n = 26) and healthy controls (control group; n = 25) using a mass spectrometry-based method. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | DSM-IV diagnosed MDD |
Sample size | 51 |
Tissue | Peripheral; Blood; Plasma; |
Platform | MS-based; LC-MS: DIONEX U3000 HPLC system with 3200 QTRAP MS system; |
PMID | |
DOI | |
Citation | Xu HB, Fang L, Hu ZC, et al. Potential clinical utility of plasma amino acid profiling in the detection of major depressive disorder. Psychiatry Res 2012;200(2-3):1054-7. |
Metabolite |
