Study M854
Study name | Liu DY 2021b |
Title | From molecular to behavior: higher order occipital cortex in major depressive disorder |
Overall design | In this study, the amplitude of low-frequency fluctuations of the blood oxygen level-dependent signal in middle temporal (MT), MT-seeded functional connectivity, and gamma-aminobutyric acid in MT were investigated in patients with major depressive disorder (MDD), using high-field 7 T magnetic resonance imaging (MRI), including resting state functional MRI and proton magnetic resonance spectroscopy. A cohort of adult MDD subjects (MDD group, n = 18) and age- and gender-matched healthy subjects (control group, n = 32) was recruited. Metabolite quantification was reported in absolute concentrations. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | DSM-V diagnosed MDD, HAMD-17 >= 18 |
Sample size | 50 |
Tissue | Central; Brain; Occipital cortex; |
Platform | MRS; MRS: 7 T whole body MR system (Siemens Healthcare, Erlangen, Germany); |
PMID | |
DOI | |
Citation | Liu DY, Ju X, Gao Y, et al. From molecular to behavior: higher order occipital cortex in major depressive disorder. Cereb Cortex. 2021 Oct 6:bhab343. |
Metabolite |
