Study M814
Study name | Zhang XL 2021 |
Title | [Regulatory effects of Ginkgo biloba extract on peripheral serum metabolite profile of mice with depression-like behavior] |
Overall design | The aim of this study was to investigate the effects of Ginkgo biloba extract on chronic social defeat stress (CSDS)-induced depression-like behavior in mice. C57BL/6J mice were divided into the following 2 groups: (1) control group (no stress, n = 5), and (2) CSDS group (10 days of chronic stress, n = 8). A metabolomics method was applied in serum samples. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Mouse; C57BL/6J mouse; |
Categories of depression | Animal model; Social defeat model; Social defeat model; |
Criteria for depression | Social interaction test |
Sample size | 13 |
Tissue | Peripheral; Blood; Serum; |
Platform | MS-based; LC-MS: Waters Amide XBride HPLC and TripleTOF 5600; |
PMID | |
DOI | |
Citation | Zhang X, Cai X, Li W, et al. [Regulatory effects of Ginkgo biloba extract on peripheral serum metabolite profile of mice with depression-like behavior]. Chin Pharm J 2021;56(7):546-552. (Article in Chinese) |
Metabolite | L-Tryptophan; L-Glutamic acid; Hypoxanthine; Xanthine; Xanthosine; Oxidized glutathione; |
