Study M756
Study name | Chen HZ 2021 |
Title | Development of mass spectrometry-based relatively quantitative targeted method for amino acids and neurotransmitters: applications in the diagnosis of major depression |
Overall design | In this study, a relatively quantitative targeted method was established for metabonomics research, on the basis of hydrophilic interaction liquid chromatography (HILIC)/QQQ MS operated in MRM mode. Serum samples of 35 patients with depression (depression group) and 33 normal controls (control group) were collected and analyzed using the targeted method. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | Not reported |
Sample size | 68 |
Tissue | Peripheral; Blood; Serum; |
Platform | MS-based; LC-MS: Agilent 1200 series HPLC coupled online via electrospray ionization with an Agilent 6410 triple quadrupole mass spectrometer; |
PMID | |
DOI | |
Citation | Chen H, Xie H, Huang S, et al. Development of mass spectrometry-based relatively quantitative targeted method for amino acids and neurotransmitters: applications in the diagnosis of major depression. J Pharm Biomed Anal. 2021 Feb 5;194:113773. |
Metabolite |
