Study M731
Study name | Du Y 2021 |
Title | Plasma metabolites were associated with spatial working memory in major depressive disorder |
Overall design | The aim of this study was to identify abnormal metabolites in major depressive disorder (MDD) by metabolomics and to explore the association between differential metabolites and neurocognitive dysfunction. Plasma samples from 53 MDD patients (MDD group) and 83 sex-, gender-, BMI-matched healthy controls (control group) were collected. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) system was used to detect metabolites in those samples. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | DSM-IV diagnosed MDD |
Sample size | 136 |
Tissue | Peripheral; Blood; Plasma; |
Platform | MS-based; LC-MS: Vanquish UHPLC system (Thermo Fisher) and an Orbitrap Q Exactive HF-X mass spectrometer (Thermo Fisher); |
PMID | |
DOI | |
Citation | Du Y, Wei J, Yang X, et al. Plasma metabolites were associated with spatial working memory in major depressive disorder. Medicine. 2021 Feb 26;100(8):e24581. |
Metabolite |
