Study M647
Study name | Mitro SD 2020 |
Title | Metabolomic markers of antepartum depression and suicidal ideation |
Overall design | The aim of this study was to examine the metabolomic profile of antepartum depression and suicidal ideation during mid-pregnancy, a time of high susceptibility to mood disorders. Fasting blood were collected from 100 pregnant Peruvian women. Patients were divided into antepartum depression group (Patient Health Questionnaire-9 >=10, n = 29) and control group (no antepartum depression, Patient Health Questionnaire-9 < 10, n = 71). A total of 307 plasma metabolites were profiled using liquid chromatography-mass spectrometry. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive symptom; Depressive symptom; Depressive symptom; |
Criteria for depression | Patient Health Questionnaire-9 >=10 |
Sample size | 100 |
Tissue | Peripheral; Blood; Plasma; |
Platform | MS-based; LC-MS: Nexera X2 U-HPLC system (Shimadzu Scientific Instruments; Marlborough, MA) with Q Exactive Orbitrap mass spectrometer (Thermo Fisher Scientific; Waltham, MA); |
PMID | |
DOI | |
Citation | Mitro SD, Larrabure-Torrealva GT, Sanchez SE, et al. Metabolomic markers of antepartum depression and suicidal ideation. J Affect Disord. 2020;262:422-428. |
Metabolite |
