Study M577
Study name | Zhang FL 2019 |
Title | Artificial intelligence based discovery of the association between depression and chronic fatigue syndrome |
Overall design | The aim of this study was to identify candidate biomarkers of depression and chronic fatigue syndrome. A total of 295 general participants were recruited to complete Zung Self-Rating Depression Scales and Chalder Fatigue Scales. Forty-one male depression patients (male depression group), 120 male non-depression participants (male control group), 56 female depression patients (female depression group), and 78 female non-depression participants (female control group) were recruited. Plasma and urine samples were used for H NMR-metabolic profiling. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive symptom; Depressive symptom; Depressive symptom; |
Criteria for depression | Depressive symptom |
Sample size | 295 |
Tissue | Peripheral; Blood; Plasma; Peripheral; Urine; Urine; |
Platform | NMR; NMR: 700 MHz Bruker Avance DRX spectrometer; |
PMID | |
DOI | |
Citation | Zhang F, Wu C, Jia C, et al. Artificial intelligence based discovery of the association between depression and chronic fatigue syndrome. J Affect Disord. 2019;250:380-390. |
Metabolite | Citric acid; Glycerol; 3-Hydroxybutyric acid; L-Valine; L-Leucine; L-Proline; L-Glutamic acid; L-Serine; L-Threonine; L-Isoleucine; L-Lactic acid; L-Alanine; L-Glutamine; L-Aspartic acid; L-Lysine; Hippuric acid; 4-Aminohippuric acid; L-Tyrosine; D-Glucose; Urea; Phenylacetylglycine; Creatinine; Indoxyl sulfate; Taurine; Pyruvic acid; Creatine; Acetic acid; N-Acetyl-L-glutamic acid; N-Acetylglutamine; Indolelactic acid; L-Histidine; cis-Aconitic acid; Isocitric acid; alpha-D-Glucose; 1-Methylhistidine; Acetoacetic acid; Dimethylamine; 1-Methylnicotinamide; Sarcosine; Alpha-Hydroxyisobutyric acid; Isobutyric acid; Formic acid; Guanidoacetic acid; Trigonelline; 3-Methylhistidine; Methylsuccinic acid; Succinylacetone; N-Nitrosodimethylamine; |
