Study M510
Study name | Liu LY 2018 |
Title | Blood and urinary metabolomic evidence validating traditional Chinese medicine diagnostic classification of major depressive disorder |
Overall design | The purpose of this study was to examine whether metabolomic variables could differentiate traditional Chinese medicine (TCM) diagnostic subtypes of MDD. Fifty medication-free patients who were experiencing a recurrent depressive episode were classified into Liver Qi Stagnation (LQS, n = 30) and Heart and Spleen Deficiency (HSD, n = 20) subtypes according to TCM diagnosis. Healthy volunteers (n = 28) were included as controls. Gas chromatography-mass spectrometry (GC-MS) was used to examine serum and urinary metabolomic profiles. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | DSM-5 diagnosed MDD, HAMD-24 >= 21 |
Sample size | 78 |
Tissue | Peripheral; Urine; Urine; Peripheral; Blood; Serum; |
Platform | MS-based; GC-MS: Varian 450-GC/240-MS; |
PMID | |
DOI | |
Citation | Liu LY, Zhang HJ, Luo LY, et al. Blood and urinary metabolomic evidence validating traditional Chinese medicine diagnostic classification of major depressive disorder. Chin Med. 2018 Oct 25;13:53. |
Metabolite |
