Study M297
Study name | Song Z 2012 |
Title | [Decreased occipital GABA concentrations in patients with first-episode major depressive disorder: a magnetic resonance spectroscopy study] |
Overall design | The aim of this study was to measure GABA concentration in the occipital cortex in major depressive disorder (MDD). A group of medication-naive, first episode depressed patients (depression group, n = 18, HAMD > 17), and a group of healthy controls (control group, n = 23) were investigated using a Point Resolved Spectroscopy (MEGA-PRESS) on a 3.0 T MR scanner. Metabolite quantification was reported in absolute concentrations. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | DSM-IV diagnosed MDD, HAMD-17 > 17, BDI > 20 |
Sample size | 41 |
Tissue | Central; Brain; Occipital cortex; |
Platform | MRS; MRS: Siemens Trio 3.0 T MR scanner; |
PMID | |
DOI | |
Citation | Song Z, Huang P, Qiu L, et al. [Decreased occipital GABA concentrations in patients with first-episode major depressive disorder: a magnetic resonance spectroscopy study]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2012;29(2):233-6. (Article in Chinese) |
Metabolite |
