Study M163
Study name | Ogawa S 2014 |
Title | Plasma L-tryptophan concentration in major depressive disorder: new data and meta-analysis |
Overall design | The aims of the present study were 2-fold: to examine whether plasma tryptophan concentration is different between Japanese patients with major depressive disorder (MDD) and controls, and to perform meta-analysis on previous studies, to determine whether plasma tryptophan concentration is lowered in MDD patients. The case-control study included 66 patients with MDD (MDD group) and 82 healthy controls (control group). Plasma tryptophan concentration was measured using the liquid chromatography/mass spectrometry (LC-MS). |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | DSM-IV diagnosed MDD |
Sample size | 148 |
Tissue | Peripheral; Blood; Plasma; |
Platform | MS-based; LC-MS: not reported; |
PMID | |
DOI | |
Citation | Ogawa S, Fujii T, Koga N, et al. Plasma L-tryptophan concentration in major depressive disorder: new data and meta-analysis. J Clin Psychiatry 2014;75(9):e906-15. |
Metabolite |
