Study M1013
Study name | Yun YJ 2022 |
Title | Relationship between the tryptophan-kynurenine pathway and painful physical symptoms in patients with major depressive disorder |
Overall design | The aim of this study was to investigate the relationship between the tryptophan-kynurenine pathway and painful physical symptoms in major depressive disorder (MDD). This study recruited 84 patients with depression (MDD group) and 46 healthy controls (control group). The serum levels of tryptophan, kynurenine, kynurenic acid, quinolinic acid, and serotonin were quantified by liquid chromatography/tandem mass spectrometry. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | ICD-10 diagnosed MDD, HAMD-17 >= 18 |
Sample size | 130 |
Tissue | Peripheral; Blood; Serum; |
Platform | MS-based; LC-MS: not reported; |
PMID | |
DOI | |
Citation | Yun Y, Zhang Q, Zhao W, et al. Relationship between the tryptophan-kynurenine pathway and painful physical symptoms in patients with major depressive disorder. J Psychosom Res. 2022 Dec;163:111069. |
Metabolite |
