Study M005
Study name | Li ZY 2010 |
Title | Study of plasma metabolic profiling and biomarkers of chronic unpredictable mild stress rats based on gas chromatography/mass spectrometry |
Overall design | In this study, a metabolomic investigation of chronic unpredictable mild stress (CUMS) rats was carried out. Plasma obtained from Sprague-Dawley rats treated by CUMS was analyzed using gas chromatography-mass spectrometry. Rats were divided into the following two groups (n = 6 in each group): (1) CUMS group and (2) control group. The CUMS stress procedure lasted for 4 weeks. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Rat; Sprague-Dawley rat; |
Categories of depression | Animal model; Chronic mild stress model; Chronic mild stress model; |
Criteria for depression | Sucrose preference test |
Sample size | 12 |
Tissue | Peripheral; Blood; Plasma; |
Platform | MS-based; GC-MS: Polaris Q ion trap mass spectrometer (Thermo Fisher Scientific Inc., USA); |
PMID | |
DOI | |
Citation | Li ZY, Zheng XY, Gao XX, et al. Study of plasma metabolic profiling and biomarkers of chronic unpredictable mild stress rats based on gas chromatography/mass spectrometry. Rapid Commun Mass Spectrom 2010;24(24):3539-46. |
Metabolite | Linoleic acid; Stearic acid; Palmitic acid; L-Tryptophan; |
