Study M906
Study name | Tateishi H 2022 |
Title | Changes in the metabolites of cerebrospinal fluid induced by rTMS in treatment-resistant depression: a pilot study |
Overall design | The aim of this study was to analyze changes in cerebrospinal fluid (CSF) metabolites in patients with treatment-resistant depression (TRD) after repetitive transcranial magnetic stimulation (rTMS). Five patients with TRD were enrolled in a high frequency (10-Hz) rTMS study. The concentrations of 72 CSF metabolites were measured at baseline and at the end of the 6-week rTMS treatment. Two patients were classified as remitter after treatment. |
Study Type | Type2; Type4; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Treatment-resistant depression; Treatment-resistant depression; |
Criteria for depression | DSM-5 diagnosed MDD |
Sample size | 5 |
Tissue | Central; Cerebrospinal fluid; Cerebrospinal fluid; |
Platform | MS-based; LC-MS: LCMS-8060 (Shimadzu Corp., Kyoto, Japan); |
PMID | |
DOI | |
Citation | Tateishi H, Setoyama D, Kato TA, et al. Changes in the metabolites of cerebrospinal fluid induced by rTMS in treatment-resistant depression: a pilot study. Psychiatry Res. 2022 Jul;313:114636. |
Metabolite |
