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Study M893

Study name

Lang J 2021

Title

Predicting hair cortisol and cortisone concentration in postpartum women through repeated measurements of perceived stress

Overall design

The aim of this study was to investigate whether hair cortisol and hair cortisone can be predicted by repeated stress reports from postpartum women in different mental health conditions. A total of 240 mothers were monitored. Among them, 141 remained non-depressed (control group) during the postpartum period (12 week), while 36 developed postpartum depression (postpartum depression group). Hair cortisol and hair cortisone were assessed via triple mass spectrometry after liquid chromatographic separation.

Study Type

Type1;

Data available

Unavailable

Organism

Human;

Categories of depression

Depressive disorder; Postpartum depression; Postpartum depression;

Criteria for depression

DSM-5 diagnosed postpartum depression

Sample size

177

Tissue

Peripheral; Hair; Hair;

Platform

MS-based; LC-MS: Agilent Technologies 1200 infinity series—QTRAP 5500 (ABSciex, Darmstadt, Germany);

PMID

34940573

DOI

10.3390/metabo11120815

Citation

Lang J, Stickel S, Gaum PM, et al. Predicting hair cortisol and cortisone concentration in postpartum women through repeated measurements of perceived stress. Metabolites. 2021 Nov 29;11(12):815.

Metabolite

Cortisol/Cortisone ratio;