Study M871
Study name | Kang M 2021 |
Title | Loneliness, circulating endocannabinoid concentrations, and grief trajectories in bereaved older adults: a longitudinal study |
Overall design | This study examined the association between loneliness and circulating endocannabinoid concentrations in grieving older adults and explored the role of endocannabinoids on the association between baseline loneliness and grief symptom trajectories. A total of 64 adults (grief with high loneliness group, HAM-D mean score 18.8, n = 18; grief with low loneliness group, HAM-D mean score 10.0, n = 26; and control group, HAM-D mean score 3.0, n = 20) completed baseline clinical assessments. Baseline circulating endocannabinoid (N-arachidonoylethanolamine and 2-arachidonoylglycerol) concentrations were quantified in the serum using liquid chromatography-mass spectrometry. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive symptom; Depressive symptom; Depressive symptom; |
Criteria for depression | Geriatric depressive symptom |
Sample size | 64 |
Tissue | Peripheral; Blood; Serum; |
Platform | MS-based; LC-MS: not reported; |
PMID | |
DOI | |
Citation | Kang M, Bohorquez-Montoya L, McAuliffe T, et al. Loneliness, circulating endocannabinoid concentrations, and grief trajectories in bereaved older adults: a longitudinal study. Front Psychiatry. 2021 Dec 8;12:783187. |
Metabolite |
