Study M805
Study name | Hamers PCM 2021 |
Title | Hair glucocorticoids in adults with intellectual disabilities and depressive symptoms pre- and post-bright light therapy: first explorations |
Overall design | The aim of this study was to explore long-term biological stress levels, assessed by hair cortisol and cortisone concentrations, in adults with intellectual disabilities and depressive symptoms and to investigate the effects of bright light therapy on hair glucocorticoids. Scalp hair samples (n = 14) were retrospectively examined at baseline and post-bright light therapy (10.000 and 300 lux). Liquid chromatography-tandem mass spectrometry was used to measure hair glucocorticoids. |
Study Type | Type2; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive symptom; Depressive symptom with comorbidity; Depressive symptom with comorbidity; |
Criteria for depression | Depressive Mood subscale of the Dutch ADAMS >= 14 |
Sample size | 14 |
Tissue | Peripheral; Hair; Hair; |
Platform | MS-based; LC-MS: not reported; |
PMID | |
DOI | |
Citation | Hamers PCM, Savas M, van Rossum EFC, et al. Hair glucocorticoids in adults with intellectual disabilities and depressive symptoms pre- and post-bright light therapy: first explorations. J Appl Res Intellect Disabil. 2021 May 28. |
Metabolite |
