Study M748
Study name | Taniguchi E 2021 |
Title | Photoperiodic changes in hippocampal neurogenesis and plasma metabolomic profiles in relation to depression-like behavior in mice |
Overall design | The aim of this study was to examine the effects of photoperiod on plasma metabolomic profiles in relation to depression-like behavior to understand a possible linkage between peripheral metabolism and behavior. C57BL/6 J mice were divided into the following 2 groups: (1) long-day group (light-dark cycle of 16 h and 8 h for three weeks), and (2) short-day group (light-dark cycle of 8 h and 16 h for three weeks). Mice in the short-day group showed longer immobility than the long-day group. Three plasma samples per group were used for metabonomic analysis. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Mouse; C57BL/6 J mouse; |
Categories of depression | Animal model; Other animal model; Other animal model; |
Criteria for depression | Forced swimming test |
Sample size | 6 |
Tissue | Peripheral; Blood; Plasma; |
Platform | MS-based; LC-MS: not reported; |
PMID | |
DOI | |
Citation | Taniguchi E, Tashiro A, Hattori A, et al. Photoperiodic changes in hippocampal neurogenesis and plasma metabolomic profiles in relation to depression-like behavior in mice. Behav Brain Res. 2021 Apr 9;403:113136. |
Metabolite | Dimethylglycine; L-Kynurenine; Trimethylamine N-oxide; 2-Hydroxybutyric acid; Argininosuccinic acid; N-Acetyl-L-alanine; |
