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Study M703

Study name

Jahangard L 2019

Title

Prenatal and postnatal hair steroid levels predict post-partum depression 12 weeks after delivery

Overall design

The aim of this study was to compare the hair steroid levels of women 12 weeks before and after delivery and with or without post-partum depression. A total of 48 women with PPD (post-partum depression group) and 50 healthy controls (control group) completed questionnaires on depressive symptoms within 12 weeks after delivery. Hair steroids were assessed using mass spectrometry.

Study Type

Type1;

Data available

Unavailable

Organism

Human;

Categories of depression

Depressive disorder; Postpartum depression; Postpartum depression;

Criteria for depression

DSM-IV diagnosed postpartum depression, EPDS >= 12, BDI >= 20

Sample size

98

Tissue

Peripheral; Hair; Hair;

Platform

MS-based; LC-MS: Shimadzu HPLC-tandem mass spectrometry system (Shimadzu, Canby, OR, USA) with AB Sciex API 5000 Turbo-ion-spray triple quadrupole tandem mass spectrometer (AB Sciex, Foster City, CA, USA);

PMID

31450789

DOI

10.3390/jcm8091290

Citation

Jahangard L, Mikoteit T, Bahiraei S, et al. Prenatal and postnatal hair steroid levels predict post-partum depression 12 weeks after delivery. J Clin Med. 2019;8(9):1290.

Metabolite

Cortisol;

Progesterone;

Cortisone;