Study M686
Study name | Zhao SG 2020 |
Title | Feature of heart rate variability and metabolic mechanism in female college students with depression |
Overall design | The aim of this study was to explore the effects of depression on cardiac autonomic nerve function and related metabolic pathways, the heart rate variability (HRV) and urinary differential metabolites were detected on the college students with depression. Twelve female freshmen with depression (depression group) were filtered by the Beck Depression Inventory (BDI-II) and Self-rating Depression Scale (SDS). Additionally, 12 healthy female students form the same grade were recruited as the control group (control group). Liquid chromatography-mass spectrometry (LC-MS) was used to detect their urinary differential metabolites. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive symptom; Depressive symptom; Depressive symptom; |
Criteria for depression | BDI-II score >= 15 and SDS score >= 50 |
Sample size | 24 |
Tissue | Peripheral; Urine; Urine; |
Platform | MS-based; LC-MS: UHPLC system (1290, Agilent Technologies) with Q Exactive mass spectrometer (Orbitrap MS, Thermo); |
PMID | |
DOI | |
Citation | Zhao S, Chi A, Yan J, et al. Feature of heart rate variability and metabolic mechanism in female college students with depression. Biomed Res Int. 2020;2020:5246350. |
Metabolite | Azelaic acid; Dimethylglycine; Hydroxyphenyllactic acid; 3-Hydroxyhippuric acid; Glycoursodeoxycholic acid; Gentisic acid; Dihydrothymine; 3-Methyluridine; m-Cresol; |
