Study M579
Study name | Zhang L 2019 |
Title | A preliminary study of uric metabolomic alteration for postpartum depression based on liquid chromatography coupled to quadrupole time-of-flight mass spectrometry |
Overall design | In this study, an LC-Q-TOF-MS-based uric metabolomic study was carried out to find out new metabolomic alterations associated with postpartum depression. There are 49 postpartum depressed patients (postpartum depression group) and 50 mentally healthy controls (control group) participated in this study. The metabolomic data of 40 patients and 40 controls were used for multivariate statistical analysis, and the data of the remaining 9 patients and 10 controls were employed for T-prediction. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Postpartum depression; Postpartum depression; |
Criteria for depression | ICD-10 diagnosed postpartum depression, HAMD-17 > 17 |
Sample size | 99 |
Tissue | Peripheral; Urine; Urine; |
Platform | MS-based; LC-MS: 1290 LC and 6540 mass system (Agilent Technology, USA); |
PMID | |
DOI | |
Citation | Zhang L, Zou W, Huang Y, et al. A preliminary study of uric metabolomic alteration for postpartum depression based on liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. Dis Markers. 2019;2019:4264803. |
Metabolite | Glutaric acid; L-Alanine; L-Tyrosine; 5-Hydroxyindoleacetic acid; Vanillylmandelic acid; Methylmalonic acid; |
