Study M561
Study name | Papadopoulou Z 2019 |
Title | Unraveling the serum metabolomic profile of post-partum depression |
Overall design | To investigate the underlying molecular correlates of post-partum depression (PPD) in peripheral material, the authors compared the serum metabolomes of an in detail characterized group of mothers suffering from PPD and a control group of mothers. Ten mothers with PPD (Edinburgh Postpartum Depression Scale >= 13) and 10 mothers without PPD were recruited. Serum samples were analyzed by a mass spectrometry platform for targeted metabolomics, based on selected reaction monitoring (SRM), which measures the levels of up to 300 metabolites. |
Study Type | Type1; |
Data available | https://www.frontiersin.org/articles/10.3389/fnins.2019.00833/full |
Organism | Human; |
Categories of depression | Depressive symptom; Depressive symptom; Depressive symptom; |
Criteria for depression | Edinburgh Postpartum Depression Scale >= 13 |
Sample size | 20 |
Tissue | Peripheral; Blood; Serum; |
Platform | MS-based; LC-MS: Prominence UFCL HPLC system with 5500 QTRAP triple quadrupole mass spectrometer; |
PMID | |
DOI | |
Citation | Papadopoulou Z, Vlaikou A, Theodoridou D, et al. Unraveling the serum metabolomic profile of post-partum depression. Front Neurosci. 2019;13:833. |
Metabolite |
