Study M543
Study name | Henriksson HE 2019 |
Title | Blood plasma metabolic profiling of pregnant women with antenatal depressive symptoms |
Overall design | The aim of this study was to investigate whether untargeted gas chromatography-mass spectrometry (GC-MS) plasma metabolomics in 45 women in late pregnancy could indicate metabolic differences between women with and without depressive symptoms. Furthermore, seasonal differences in the metabolic profiles were explored. Plasma samples were collected from summer controls (summer control group, n = 10), summer cases (summer depression group, n = 7), winter controls (winter control group, n = 20), and winter cases (winter depression group, n = 8). |
Study Type | Type1; |
Data available | |
Organism | Human; |
Categories of depression | Depressive symptom; Depressive symptom; Depressive symptom; |
Criteria for depression | Edinburgh Postnatal Depression Scale>= 12 |
Sample size | 45 |
Tissue | Peripheral; Blood; Plasma; |
Platform | MS-based; GC-MS: Saturn 2200 ion-trap GC-MS (formerly Varian Inc., now Bruker (GC)/Agilent (MS)); |
PMID | |
DOI | |
Citation | Henriksson HE, Malavaki C, Brann E, et al. Blood plasma metabolic profiling of pregnant women with antenatal depressive symptoms. Transl Psychiatry. 2019;9(1):204. |
Metabolite | Glyceric acid; |
