Study M508
Study name | Adachi Y 2019 |
Title | Association between plasma alpha-aminobutyric acid and depressive symptoms in older community-dwelling adults in Japan |
Overall design | The aim of this study was to examine the association between depressive symptoms and plasma amino acid related metaboli in older adults. A total of 119 older adults aged >= 65 years (depressive group, n = 22; non-depressive group, n = 97) were used for analysis. Depressive symptoms were evaluated using the Geriatric Depression Scale-15, which has been validated in older community-dwelling individuals, and used a cut off score of >= 5 to classify participants as having depressive symptoms. High-performance liquid chromatography-electrospray ionization mass spectrometry was used to measure the concentrations of plasma amino acid-related metabolites. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive symptom; Depressive symptom; Depressive symptom; |
Criteria for depression | Geriatric Depression Scale-15 >= 5 |
Sample size | 119 |
Tissue | Peripheral; Blood; Plasma; |
Platform | MS-based; LC-MS: not reported; |
PMID | |
DOI | |
Citation | Adachi Y, Toyoshima K, Nishimoto R, et al. Association between plasma alpha-aminobutyric acid and depressive symptoms in older community-dwelling adults in Japan. Geriatr Gerontol Int. 2019 Mar;19(3):254-258. |
Metabolite |
