Study M468
Study name | Cheng X 2016 |
Title | [Health Qigong Wuqinxi improves hydrogen proton magnetic resonance spectra in prefrontal cortex and hippocampus in college students with mild depression] |
Overall design | The aim of this study was to investigate the effects of health Qigong Wuqinxi exercise on mild depression in college students and analyze the changes in hydrogen proton magnetic resonance spectra (1H-MRS) in the prefrontal cortex and hippocampus after the exercise. Fifty-eight volunteer college students, including 30 with mild depression and 28 healthy students, were randomized into the intervention group and non-intervention group. The students in the intervention group were asked to practice health Qigong Wuqinxi training for 12 weeks and those in the non-intervention group did not engage in such training. For each subject, BECK Depression Self-reported questionnaire (BDI), Hamilton Depression rating scale (HAMD) score, and the metabolic parameters of 1H-MRS in the prefrontal cortex and hippocampus were evaluated before and after the intervention. Metabolite quantification was reported relative to total creatine as the reference peak. |
Study Type | Type1; Type2; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | DSM-IV diagnosed MDD |
Sample size | 58 |
Tissue | Central; Brain; Prefrontal cortex; Central; Brain; Hippocampus; |
Platform | MRS; MRS: 3.0 Tesla MRI system (Philips); |
PMID | |
DOI | |
Citation | Cheng X, Wang DM, Chen X, et al. [Health Qigong Wuqinxi improves hydrogen proton magnetic resonance spectra in prefrontal cortex and hippocampus in college students with mild depression]. Nan Fang Yi Ke Da Xue Xue Bao. 2016,20;36(11):1468-76. |
Metabolite | N-Acetyl aspartate/(Creatine and Phosphocreatine) ratio; Choline-containing compounds/(Creatine and Phosphocreatine) ratio; |
