Study M461

Study name

Yoo CH 2018

Title

Metabolic effects of light deprivation in the prefrontal cortex of rats with depression-like behavior: In vivo proton magnetic resonance spectroscopy at 7T

Overall design

Metabolic effects of light deprivation in the prefrontal cortex of rats with depression-like behavior: in vivo proton magnetic resonance spectroscopy at 7T

Study Type

Type1;

Data available

Unavailable

Organism

Rat; Sprague-Dawley rat;

Categories of depression

Animal model; Other animal model; Other animal model;

Criteria for depression

Forced swimming test

Sample size

20

Tissue

Central; Brain; Prefrontal cortex;

Platform

MRS; MRS: PharmaScan 7T MRI system (Bruker BioSpin Corporation, Billerica, MA, USA);

PMID

29501652

DOI

10.1016/j.brainres.2018.02.047

Citation

Yoo CH, Song KH, Lim SI, et al. Metabolic effects of light deprivation in the prefrontal cortex of rats with depression-like behavior: in vivo proton magnetic resonance spectroscopy at 7T. Brain Res 2018.

Metabolite

myo-Inositol;

L-Glutamic acid;

Phosphocreatine;

Glutamate and Glutamine;

Creatine and Phosphocreatine;