Study M347
Study name | Taylor R 2017 |
Title | Neurometabolic abnormalities in schizophrenia and depression observed with magnetic resonance spectroscopy at 7 T |
Overall design | The aim of this study was to measure metabolite concentrations within the anterior cingulate cortex (ACC) and thalamus of people with schizophrenia and people with major depressive disorder (MDD). Spectra were acquired from 16 volunteers with schizophrenia, 17 with MDD (depression group) and 18 healthy controls (control group) using magnetic resonance spectroscopy on a 7 Tesla scanner. Metabolite quantification was reported relative to brain water concentration. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | DSM-IV diagnosed MDD |
Sample size | 35 |
Tissue | Central; Brain; Anterior cingulate cortex; Central; Brain; Thalamus; |
Platform | MRS; MRS: 7 T Agilent/Magnex head-only MRI (Agilent, Inc., Walnut Creek, California, USA); |
PMID | |
DOI | |
Citation | Taylor R, Osuch EA, Schaefer B, et al. Neurometabolic abnormalities in schizophrenia and depression observed with magnetic resonance spectroscopy at 7 T. BJPsych Open 2017;3(1):6-11. |
Metabolite |
