Study M230
Study name | Michael N 2003b |
Title | Metabolic changes after repetitive transcranial magnetic stimulation (rTMS) of the left prefrontal cortex: a sham-controlled proton magnetic resonance spectroscopy (1H MRS) study of healthy brain |
Overall design | The aim of this study was to assess metabolic changes by proton magnetic resonance spectroscopy following high-frequency rapid transcranial magnetic stimulation (20 Hz), both immediately after a single session and 24 h after a series of five consecutive sessions. Twelve healthy volunteers were enrolled in a prospective single-blind, randomized study (sham group, n = 5; rTMS group, n = 7). Three brain regions were investigated (right, left dorsolateral prefrontal cortex, left anterior cingulate cortex). Metabolite quantification was reported in institutional units. |
Study Type | Type3; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Healthy individuals; Healthy individuals; Healthy individuals; |
Criteria for depression | Not reported |
Sample size | 12 |
Tissue | Central; Brain; Anterior cingulate cortex; Central; Brain; Dorsolateral prefrontal cortex; |
Platform | MRS; MRS: 1.5 T MR (Magnetom SP, Siemens, Erlangen, FRG); |
PMID | |
DOI | |
Citation | Michael N, Gosling M, Reutemann M, et al. Metabolic changes after repetitive transcranial magnetic stimulation (rTMS) of the left prefrontal cortex: a sham-controlled proton magnetic resonance spectroscopy (1H MRS) study of healthy brain. Eur J Neurosci 2003;17(11):2462-8. |
Metabolite |
