Study M194
Study name | Li CX 2008b |
Title | [Cerebral metabolic changes in prefrontal cortex of depression-like rat model with long-term chronic forced swimming studied by ex vivo high resolution 1H NMR] |
Overall design | The aim of this study was to evaluate the face and construct the validity of the depression-like rat model with long-term (4 weeks) chronic forced swimming (CFSS), the cerebral metabolic changes of prefrontal cortex (PFC) were studied by ex vivo high resolution 1H NMR as well as behavior tests. Rats were divided into the following 2 groups: (1) control group (n = 11), and (2) CFSS group (chronic forced swimming stress, n = 15). The CFSS stress procedure lasted for 4 weeks. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Rat; Wistar rat; |
Categories of depression | Animal model; Other animal model; Other animal model; |
Criteria for depression | Sucrose preference test |
Sample size | 26 |
Tissue | Central; Brain; Prefrontal cortex; |
Platform | NMR; NMR: Varian INOVA-500 spectrometer; |
PMID | |
DOI | |
Citation | Li CX, Wang YQ, Pan WJ, et al. [Cerebral metabolic changes in prefrontal cortex of depression-like rat model with long-term chronic forced swimming studied by ex vivo high resolution 1H NMR]. Journal of Wuhan University 2008;54(4):451-6. (Article in Chinese) |
Metabolite |
