Study M1127
Study name | Choi J 2022 |
Title | Effects of flavonoid-rich orange juice intervention on major depressive disorder in young adults: a randomized controlled trial |
Overall design | The aim of this study was to assess the effects of flavonoid-rich orange juice on the major depressive disorder (MDD) using a randomized controlled trial. In this study, 40 patients with MDD were randomly assigned to a flavonoid-rich orange juice group and a flavonoid-low orange cordial group. The HAMD-17, BDI-II, and CES-D scores of the two groups significantly decreased after 8-week treatment, indicating an improvement in MDD scores. The subjects provided fecal specimens before and after the 8-week treatment. Six short-chain fatty acids were analyzed by LC-MS/MS. |
Study Type | Type2; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | MINI-Plus diagnosed MDD |
Sample size | 40 |
Tissue | Peripheral; Faece; Faece; |
Platform | MS-based; LC-MS: not reported; |
PMID | |
DOI | |
Citation | Choi J, Kim JH, Park M, et al. Effects of flavonoid-rich orange juice intervention on major depressive disorder in young adults: a randomized controlled trial. Nutrients. 2022 Dec 28;15(1):145. |
Metabolite |
