Study name | Wang Y 2023 |
Title | Disturbances of phosphatidylcholines metabolism in major depressive disorder |
Overall design | The aim of this study was to capture the potential lipid metabolites in plasma for major depressive disorder (MDD) diagnostic approach. A total of 42 drug-naive MDD patients (MDD group) and 49 healthy individuals (control group) were recruited. Lipid metabolism-related molecules in plasma were measured by liquid chromatography-mass spectrometry. |
Type1; | |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive disorder; Depression; Depression; |
Criteria for depression | DSM-IV-TR diagnosed MDD |
Sample size | 91 |
Tissue | Peripheral; Blood; Plasma; |
Platform | MS-based; LC-MS: not reported; |
PMID | |
DOI | |
Citation | Wang Y, Chen X, Chen Z, et al. Disturbances of phosphatidylcholines metabolism in major depressive disorder. CNS Spectr. 2023 Jan 17;1-9. |
Metabolite | Taurocholic acid; Glycocholic acid; PC(32:0); Glycoursodeoxycholic acid; PC(16:0/18:0); 1-heptadecanoyl-sn-glycero-3-Phosphocholine; |