Study M1057
Study name | Laketic K 2023 |
Title | Maternal metabolites indicative of mental health status during pregnancy |
Overall design | The aim of this study was to examine whether maternal serum metabolite signatures could distinguish between healthy controls and individuals with symptoms of depression and anxiety. Mental health was assessed using the Edinburgh Perinatal Depression Scale (EPDS). Participants were stratified into two categories: unlikely to have depression (EPDS <13; control group; n = 65), and probable depression (EPDS >= 13; depression group; n = 34). Serum samples, collected from 28-32 weeks of gestation, were evaluated by nuclear magnetic resonance spectroscopy. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Human; |
Categories of depression | Depressive symptom; Depressive symptom; Depressive symptom; |
Criteria for depression | Edinburgh Perinatal Depression Scale >= 13 |
Sample size | 99 |
Tissue | Peripheral; Blood; Serum; |
Platform | NMR; NMR: Bruker 600 MHz Avance II spectrometer (600.22 MHz, 5 mm TXI probe, 298 K. Billerica, MA, USA); |
PMID | |
DOI | |
Citation | Laketic K, Lalonde-Bester S, Smyth K, et al. Maternal metabolites indicative of mental health status during pregnancy. Metabolites. 2022 Dec 23;13(1):24. |
Metabolite | 3-Hydroxybutyric acid; |
