Study M016
Study name | Liu XJ 2012b |
Title | Urinary metabonomic study using a CUMS rat model of depression |
Overall design | In this study, a urinary metabonomics method based on the NMR spectrometry was used to study the metabolic perturbation in chronic unpredictable mild stress (CUMS)-induced rat depression model. Rats were divided into 2 groups (n = 6 in each group): (1) control group and (2) CUMS group. The CUMS stress procedure lasted for 3 weeks. |
Study Type | Type1; |
Data available | Unavailable |
Organism | Rat; Sprague-Dawley rat; |
Categories of depression | Animal model; Chronic mild stress model; Chronic mild stress model; |
Criteria for depression | Sucrose preference test |
Sample size | 12 |
Tissue | Peripheral; Urine; Urine; |
Platform | NMR; NMR: Varian VNMRS-600 MHz NMR spectrometer (Varian Inc., USA); |
PMID | |
DOI | |
Citation | Liu XJ, Li ZY, Li ZF, et al. Urinary metabonomic study using a CUMS rat model of depression. Magn Reson Chem 2012;50(3):187-92. |
Metabolite |
